Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to ...

Resection of liver metastases remains the only treatment with curative potential for metastatic colorectal cancer to the liver, but unfortunately few patients are eligible for the surgery. For ...

UAB Medicine offers liver transplantation as a treatment for metastatic colorectal cancer, expanding access to advanced ...

Colon cancer is increasingly affecting younger adults, often going undetected until it spreads. Andrew Sweeney, aware of his family history, was diagnosed with colon cancer after severe pain led to a ...

International and contrasting perspectives on early-onset colorectal cancer: Awareness, testing, and research priorities of survivors and caregivers. This is an ASCO Meeting Abstract from the 2026 ...

The Phase 2 study will investigate the potential of getacatetide to overcome β-catenin-driven immune exclusion, activate cytotoxic T cells and enhance response to checkpoint inhibition in patients ...

Drs. Pedro Barata, Yi Song, Meenakshi Jeeva, and Lauren Park discuss liver-directed therapies in colorectal cancer, ongoing developments in locoregional therapies for unresectable colorectal liver ...

Combining PDS01ADC with HAIP FUDR achieved a 77.8% 6-month ORR in nine mCRC liver-metastasis patients, compared with ~35% reported in a parallel HAIP-only experience. Two-year overall survival was ~85 ...

When David Lyon saw blood in his stool, he didn't think much of it. He was a fit 26-year-old who worked in a sheet metal shop. The spots were inconsistent, and he thought he might have just sustained ...