Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides into mitochondrial DNA (mtDNA) initiates an inflammatory cascade. Subscribe to ...
New insights into how bacteria control DNA synthesis open the door to next generation antimicrobials
Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell ...
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