Zinc is an essential trace element that controls myriad biological processes. The delicate balance of its concentration in ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

What is the endoplasmic reticulum? The endoplasmic reticulum is the single largest membrane-bound organelle found inside eukaryotic cells. Its complex structure containing tubules, sheets, and ...

How does the ER prevent misfolded proteins? Researchers identify the SLC33A1 transporter as a critical glutathione regulator ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes, transporters, ...

A fat signaling system controls the interface of cellular endoplasmic reticulum (ER) with early endosomes to regulate the shape and activity of mitochondria, and allow cells to survive periods of ...