Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...

For roughly four in every ten women whose estrogen receptor-positive breast cancer has spread and stopped responding to ...

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...

A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures called mitochondria turn ...

LA JOLLA (May 12, 2025)—A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures ...

We all learned in high school biology that mitochondria are the powerhouse of the cell. But powering up those cellular engines requires a molecular spark. Now, scientists at the Salk Institute have ...

Antibody drug conjugates treatment response score (ADC TRS) for sequencing trastuzuamb deruxtecan (T-DXd) and sacituzumab govitecan (SG) in advanced breast cancer (aBC). Overall survival in patients ...

Chronic kidney disease (CKD) affects more than 10% of the global population and is expected to become the fifth leading cause of death worldwide within the next two decades. Perhaps surprisingly, ...

Researchers discover that estrogen can turn on pain signals associated with conditions like irritable bowel syndrome. Women are dramatically more likely than men to suffer from irritable bowel ...

Psilocybin induces different behavioral responses in rats depending on their age and female reproductive cycles. Treating ...