Chimeric antigen receptor (CAR) therapy has transformed the treatment of certain blood cancers, but every clinically approved CAR-T cell product to date is manufactured with viral vectors that ...

Researchers at the Francis Crick Institute, King's College London and Complutense University of Madrid have shown that γδ T ...

For patients whose solid tumors have returned or continued to grow after surgery, chemotherapy, and radiation, the therapeutic landscape can feel starkly empty. A newly published phase 1 clinical ...

In the setting of Alzheimer’s and other neurodegenerative diseases, do T cells make things better, or worse? A simple answer just won’t do—it likely depends on the type of T cells, where they are in ...

Scientists analyzing human and mouse pancreatic lymph nodes (PLNs) and spleens have identified a distinct subset of CD4 memory helper T cells associated with type 1 diabetes (T1D). Reported by ...

Research on preventing type 1 diabetes often focuses on limiting the autoimmune response that destroys the body’s ability to produce its own insulin. A new technology developed by scientists at the ...

Cell therapy is an advanced biomedical approach that utilizes living cells as therapeutic agents to treat disease or repair tissue. 4 Scientists isolate cells from a patient or a healthy donor and ...