Translation by the ribosome occurs by a complex mechanism involving the coordinated interaction of multiple nucleic acid and protein ligands. Here we use zero-mode waveguides (ZMWs) and sophisticated ...

A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally ...

Cells manufacture proteins by following instructions encoded in messenger RNA, which is read in three-letter groups called codons. To translate this message, the cell uses molecules called transfer ...

Documenting the first substantial thing I did in my own lab at CU, discovery of the ability of Aminoacyl RNA Synthetases (AARS) to correct aminoacylation mistakes (simultaneous with Eldred & Schimmel, ...