Cell type annotation is the step at which spatial transcriptomics data becomes interpretable biology, converting expression matrices into labeled tissue maps. The challenge is sharpened by limited ...

A complete guide to next-generation sequencing: the chemistry behind major platforms, how libraries are built, data analyzed, ...

Artificial intelligence (AI) and machine learning are increasingly being applied in the field of RNA biology. These methods are used to predict RNA structures, interactions with proteins and small ...

Researchers at the University of Cologne, University Hospital Cologne and the Max Planck Institute for Metabolism Research ...

Plasma cell-free RNA (cfRNA) is a promising source of non-invasive biomarkers, but its clinical translation is hindered by technical challenges and a lack of protocol standardization, which ...

This manuscript examines how overexpression of sphingosine 1-phosphate receptor 1 in a mouse model affects neutrophil distribution, metabolism and function. Given the significance of S1PR1 in ...

The extracellular milieu, including extracellular vesicles (EVs), plays a pivotal role in brain development. In this study, we sought to elucidate the pathogenesis of progressive myoclonus epilepsy ...

Obesity and related metabolic disorders have surged globally, and are mechanistically interconnected through dysregulated ...

In a confrontation with an emotionally disturbed person, cops adhered to the ‘use of force continuum’ in which they were trained. A strain of rhetoric popular among a subset of very online young men ...

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